| 标题 | 杂志 | 摘要 |
Cell Culture Media Chronicle |
Biochem Pharmacol. 2021年01月 Xu WY, et al. |
This review has provided the information needed to facilitate investigators to decide an appropriate medium according to their aims. |
Soy hydrolysate mimic autocrine growth factors effect of conditioned media to promote single CHO-K1 cell proliferation |
Tissue Cell. 2021年01月 Xu WY, et al. |
Therefore, we concluded that hydrolysate can mimic the autocrine growth factor(s) effect to improve cloning efficiency observed in CM. |
Quality by Design (QbD) Concept: A Potential Solution to Chinese Current Biomanufacturing Challenges |
Biochem Pharmacol. 2021年01月 Poon HF, et al. |
QbD provide a better control strategy during the stage of design space identification. |
The Scattered Twelve Tribes of HEK293 |
Biochem Pharmacol. 2021年01月 Yuan J, et al. |
This review should provide a key reference for the HEK293 variants’ historical and developmental background. |
Analytical Approach for Biosimilar Development: Special Focus on Monoclonal Antibody Biosimilars |
Int J Biopharm Sci. 2021年01月 Yuan J, et al. |
In these review, the approach for physicochemical characterization, biological activity and impurities assessment were reviewed. |
Drugability Studies are Keys to the Successful Commercialization of Biotherapeutics |
Biochem Pharmacol. 2021年01月 Yuan J, et al. |
Drugability assessment is the key for successful biotherapeutic commercialization. Here, we reviewed current literature, and summarized the major durability studies of biotherapeutics. |